Annals of Phlebology

Table. 1.

Summary of the category, names, brand names for each venoactive drug (16,29)

Group Substance Origin Recommendation grade (2018 UIP guideline) Commercial products in Korea
Gamma-benzopyrones
(flavonoids)
Diosmin Citrus spp. 1 조아디오스민(조아제약), 디오맥스(동아제약), 베노론(한올바이오파마), 치센(동국제약)
MPFF* Rutaceae aurantiae 1 베니톨(광동제약), 플라벤정(태극제약), 프라린정(경남제약), 프라빈정(동성제약), 치벤정(영일제약)
Rutin and rutosides Sophora japonica 1 -
HR* Eucalyptus spp. 1 엘라스에이(조아제약), 케이나(삼진제약), 헤모케어(오스틴제약)
Saponins Escin Horse chestnut 1 -
Ruscus extract Butcher’s broom 1 -
Other plant extracts Anthocyans Bilberry 2C 타겐에프(국제약품)
Proanthocyanidins Maritime pine, Vitis vinifera 2C 엔테론(한림제약)
Centella asiatica Centella, Gotukola - 센시아정(동국제약)
Synthetic product Calcium dobesilate Synthetic 2 독시움(일성신약)
Naftazon Synthetic - 메디아벤(한국팜비오)

*MPFF: micronized purified flavonoid fraction, HR: 0-(b-Hydroxyethyl)-rutosides (troxerutin).

Ann Phlebology 2021;19:21~26 https://doi.org/10.37923/phle.2021.19.2.21
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